Model of beta-cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables.

@article{Magnus1998ModelOB,
  title={Model of beta-cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables.},
  author={Gerhard Magnus and Joel Keizer},
  journal={The American journal of physiology},
  year={1998},
  volume={274 4 Pt 1},
  pages={C1174-84}
}
In the preceding article [Am. J. Physiol. 274 (Cell Physiol. 43): C1158-C1173, 1998], we describe the development of a kinetic model for the interaction of mitochondrial Ca2+ handling and electrical activity in the pancreatic beta-cell. Here we describe further results of those simulations, focusing on mitochondrial variables, the rate of respiration, and fluxes of metabolic intermediates as a function of D-glucose concentration. Our simulations predict relatively smooth increases of O2… CONTINUE READING
38 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 38 extracted citations

Similar Papers

Loading similar papers…