Model membrane approaches to determine the role of calcium for the antimicrobial activity of friulimicin.

@article{RederChrist2011ModelMA,
  title={Model membrane approaches to determine the role of calcium for the antimicrobial activity of friulimicin.},
  author={Katrin Reder-Christ and Hildegard Falkenstein-Paul and Gabriela Klocek and Saad Al-Kaddah and Udo Bakowsky and Gerd Bendas},
  journal={International journal of antimicrobial agents},
  year={2011},
  volume={37 3},
  pages={256-60}
}
Friulimicin is a cyclic lipopeptide antibiotic, currently in clinical development, that possesses excellent activity against Gram-positive bacteria, including multiresistant strains. A recent study on the mode of action of friulimicin reported on the interference with bacterial cell wall biosynthesis via a calcium-dependent complexing of the bactoprenol… CONTINUE READING