Model fusion: The next phase in developing animal models for parkinson’s disease

@article{ManningBo2007ModelFT,
  title={Model fusion: The next phase in developing animal models for parkinson’s disease},
  author={Amy B. Manning-Boğ and James William Langston},
  journal={Neurotoxicity Research},
  year={2007},
  volume={11},
  pages={219-240}
}
Within the past 25 years, discoveries of environmental and monogenetic forms of parkinsonism have shaped the direction of Parkinson’s disease (PD) research and development of experimental systems to study PD. In this review, we outline a remarkable array ofin vivo models available, with particular emphasis on their benefits and pitfalls and the contribution each has made to enhance our understanding of pathological mechanisms involved in PD. Further, we discuss the increasingly popular approach… CONTINUE READING