Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application

@article{Li2001ModelbasedAO,
  title={Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application},
  author={Cheng Jiang Li and Wing Hung Wong},
  journal={Genome Biology},
  year={2001},
  volume={2},
  pages={research0032.1 - research0032.11}
}
A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe pair and calculates model-based expression indexes (MBEI). MBEI has standard error attached to it as a measure of accuracy. Here we investigate the stability of the probe-sensitivity index across different tissue types, the reproducibility of results in replicate experiments, and the use of MBEI in perfect match (PM)-only… CONTINUE READING
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