Model-Based Linkage Analysis of a Quantitative Trait.

@article{Song2017ModelBasedLA,
  title={Model-Based Linkage Analysis of a Quantitative Trait.},
  author={Yeunjoo E. Song and Sunah Song and Audrey H. Schnell},
  journal={Methods in molecular biology},
  year={2017},
  volume={1666},
  pages={
          283-310
        }
}
Linkage Analysis is a family-based method of analysis to examine whether any typed genetic markers cosegregate with a given trait, in this case a quantitative trait. If linkage exists, this is taken as evidence in support of a genetic basis for the trait. Historically, linkage analysis was performed using a binary disease trait, but has been extended to include quantitative disease measures. Quantitative traits are desirable as they provide more information than binary traits. Linkage analysis… CONTINUE READING

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