Mode of action of neuropeptides from the adipokinetic hormone family.

@article{Gde2003ModeOA,
  title={Mode of action of neuropeptides from the adipokinetic hormone family.},
  author={Gerd G{\"a}de and Lutz Auerswald},
  journal={General and comparative endocrinology},
  year={2003},
  volume={132 1},
  pages={
          10-20
        }
}
Regulation of intermediary metabolism and water balance of insects by neuropeptides.
  • G. Gäde
  • Biology
    Annual review of entomology
  • 2004
TLDR
Biosynthesis, release, receptors, mode of action, inactivation, structure-activity studies, and biological functions are discussed for the various peptides.
Neuropeptide Action in Insects and Crustaceans*
TLDR
Two studies illustrate how multiple neuropeptides allow for flexibility in response to physiological challenges in crustaceans and insects.
Functional Analysis of Adipokinetic Hormone Signaling in Bombyx mori
TLDR
The results support the hypothesis that only AKH1 and AKH2 peptides together with the AKHR1 receptor are involved in the maintenance of energy homeostasis and clarifies the role of BmAKHR1 in energyHomeostasis.
The obesity‐related Adipokinetic hormone controls feeding and expression of neuropeptide regulators of Drosophila metabolism
TLDR
Investigations of the roles of this hormone in the model organism Drosophila melanogaster have shown that this anti-obesity factor is a central regulator of fly metabolism, and controls crucial processes such as feeding, metabolic rate, storage of energy reserves, and expression of regulatory genes from the neuropeptide hormone family, including the fly homologs of human insulin.
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Calcium and cAMP are second messengers in the adipokinetic hormone-induced lipolysis of triacylglycerols in Manduca sexta fat body.
TLDR
The findings indicate that the action of adipokinetic hormone in mobilizing lipids from the insect fat body involves both cAMP and calcium as intracellular messengers.
Primary role of adipokinetic hormone in the formation of low density lipophorin in locusts.
It was demonstrated that the primary action of adipokinetic hormone (AKH) is to stimulate calcium ion uptake into the fat body cell, subsequently causing the formation of diacylglycerol from
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