Mode of Genetic Inheritance Modifies the Association of Head Circumference and Autism-Related Symptoms: A Cross-Sectional Study

@inproceedings{Davis2013ModeOG,
  title={Mode of Genetic Inheritance Modifies the Association of Head Circumference and Autism-Related Symptoms: A Cross-Sectional Study},
  author={Jonathan M. P. Davis and Jonathon G. Keeney and James M. Sikela and Susan Hepburn},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Frequently individuals with autism spectrum disorder (ASD) have been noted with a larger head circumference (HC) than their typical developing peers. Biologic hypotheses suggest that an overly rapid brain growth leads to the core symptoms of ASD by impairing connectivity. Literature is divided however where deleterious, protective and null associations of HC with ASD symptoms in individuals with ASD have been found. METHOD Individuals (n = 1,416) from the Autism Genetic Resource… CONTINUE READING
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