Mode Localization in the Cooperative Dynamics of Protein Recognition

@article{Copperman2016ModeLI,
  title={Mode Localization in the Cooperative Dynamics of Protein Recognition},
  author={Jeremy Copperman and Marina G Guenza},
  journal={Biophysical Journal},
  year={2016},
  volume={110}
}
The biological function of proteins is encoded in their structure and expressed through the mediation of their dynamics. But how do the random thermal motions of a folded protein in the picosecond timescale propagate to become emergent biological processes? Our approach is a novel theoretical method, the Langevin Equation for Protein Dynamics (LE4PD), which takes the structural ensemble of a protein as input and projects the dynamics analytically. Both simulation-derived and experimental NMR… 
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