Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.

@article{Goss2013ModafinilAT,
  title={Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.},
  author={Alexander J. Goss and M. Kaşer and S. Costafreda and B. Sahakian and C. Fu},
  journal={The Journal of clinical psychiatry},
  year={2013},
  volume={74 11},
  pages={
          1101-7
        }
}
  • Alexander J. Goss, M. Kaşer, +2 authors C. Fu
  • Published 2013
  • Medicine, Psychology
  • The Journal of clinical psychiatry
    • OBJECTIVE Current pharmacologic treatments for a depressive episode in unipolar major depressive disorder (MDD) and bipolar depression are limited by low rates of remission. [...] Key MethodDATA SOURCES MEDLINE/PubMed, PsycINFO, 1980-April 2013 were searched using the following terms: (modafinil or armodafinil) and (depressi* or depressed or major depressive disorder or major depression or unipolar or bipolar or dysthymi*).Expand Abstract
    View PDF
    Top 3 of 74 Citations
    Efficacy of off-label augmentation in unipolar depression: A systematic review of the evidence
    Julia Kleeblatt, F. Betzler, … S. KöhlerEuropean Neuropsychopharmacology2017
    9
    Optimized Treatment Strategy for Depressive Disorder.
    Peijun ChenAdvances in experimental medicine and biology2019
    2
    Aripiprazole augmentation versus antidepressant switching for patients with major depressive disorder: A 6-week, randomized, rater-blinded, prospective study.
    Changsu Han, Sheng-Min Wang, … C. PaeJournal of psychiatric research2015
    24

    Figures, Tables, and Topics from this paper.

    Figures and Tables

    Explore Further: Topics Discussed in This Paper

    74 Citations
    Fields of Study

    Fields of Study

    Citation Type

    Citation Type

    Efficacy of off-label augmentation in unipolar depression: A systematic review of the evidence
    9
    Optimized Treatment Strategy for Depressive Disorder.
    2
    Aripiprazole augmentation versus antidepressant switching for patients with major depressive disorder: A 6-week, randomized, rater-blinded, prospective study.
    24
    Treatment of neurocognitive symptoms in unipolar depression: A systematic review and future perspectives.
    25
    Managing inadequate antidepressant response in depressive illness.
    9
    Modafinil Moderates the Relationship Between Cancer-Related Fatigue and Depression in 541 Patients Receiving Chemotherapy
    12
    Cognition as a target in major depression: New developments
    51
    Challenging Treatment-Resistant Major Depressive Disorder: A Roadmap for Improved Therapeutics
    20
    The role of methylphenidate in depression
    1
    Backing into the future: pharmacological approaches to the management of resistant depression.
    16

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 39 REFERENCES
    Psychostimulants in moderate to severe affective disorder: A systematic review of randomized controlled trials
    23
    Use of adjunctive stimulants in adult bipolar depression.
    29
    A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness.
    168
    Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness.
    86
    Open-label study of adjunct modafinil for the treatment of patients with fatigue, sleepiness, and major depression treated with selective serotonin reuptake inhibitors
    12
    Modafinil augmentation of SSRI therapy in patients with major depressive disorder and excessive sleepiness and fatigue: a 12-week, open-label, extension study.
    55
    Adjunct modafinil for the short-term treatment of fatigue and sleepiness in patients with major depressive disorder: a preliminary double-blind, placebo-controlled study.
    172
    A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression.
    203
    Modafinil for Remitted Bipolar Depression with Hypersomnia
    28
    Modafinil augmentation of antidepressant treatment in depression.
    193