Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.

@article{Goss2013ModafinilAT,
  title={Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.},
  author={Alexander J. Goss and M. Kaşer and S. Costafreda and B. Sahakian and C. Fu},
  journal={The Journal of clinical psychiatry},
  year={2013},
  volume={74 11},
  pages={
          1101-7
        }
}
  • Alexander J. Goss, M. Kaşer, +2 authors C. Fu
  • Published 2013
  • Medicine, Psychology
  • The Journal of clinical psychiatry
    • OBJECTIVE Current pharmacologic treatments for a depressive episode in unipolar major depressive disorder (MDD) and bipolar depression are limited by low rates of remission. [...] Key MethodDATA SOURCES MEDLINE/PubMed, PsycINFO, 1980-April 2013 were searched using the following terms: (modafinil or armodafinil) and (depressi* or depressed or major depressive disorder or major depression or unipolar or bipolar or dysthymi*).Expand Abstract
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    References

    SHOWING 1-10 OF 39 REFERENCES
    Psychostimulants in moderate to severe affective disorder: A systematic review of randomized controlled trials
    • 22
    Use of adjunctive stimulants in adult bipolar depression.
    • 30
    • PDF
    A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness.
    • 172
    Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness.
    • 87
    Open-label study of adjunct modafinil for the treatment of patients with fatigue, sleepiness, and major depression treated with selective serotonin reuptake inhibitors
    • 12
    • PDF
    Modafinil augmentation of SSRI therapy in patients with major depressive disorder and excessive sleepiness and fatigue: a 12-week, open-label, extension study.
    • 56
    Adjunct modafinil for the short-term treatment of fatigue and sleepiness in patients with major depressive disorder: a preliminary double-blind, placebo-controlled study.
    • 176
    • PDF
    A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression.
    • 211
    Modafinil for Remitted Bipolar Depression with Hypersomnia
    • 29
    Modafinil augmentation of antidepressant treatment in depression.
    • 196