Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.

@article{Goss2013ModafinilAT,
  title={Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.},
  author={Alexander J Goss and Muzaffer Kaşer and Sergi G. Costafreda and Barbara J. Sahakian and Cynthia H. Y. Fu},
  journal={The Journal of clinical psychiatry},
  year={2013},
  volume={74 11},
  pages={
          1101-7
        }
}
OBJECTIVE Current pharmacologic treatments for a depressive episode in unipolar major depressive disorder (MDD) and bipolar depression are limited by low rates of remission. Residual symptoms include a persistent low mood and neurovegetative symptoms such as fatigue. The objective of this study was to examine the efficacy and tolerability of augmentation of first-line therapies with the novel stimulant-like agent modafinil in MDD and bipolar depression. DATA SOURCES MEDLINE/PubMed, PsycINFO… CONTINUE READING

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