Mobilization of the cell adhesion glycoprotein F3/contactin to axonal surfaces is activity dependent.

@article{Pierre2001MobilizationOT,
  title={Mobilization of the cell adhesion glycoprotein F3/contactin to axonal surfaces is activity dependent.},
  author={Karin Pierre and Bertrand Dupouy and Mathieu Allard and Dominique A. Poulain and Dionysia T. Theodosis},
  journal={The European journal of neuroscience},
  year={2001},
  volume={14 4},
  pages={645-56}
}
F3/contactin is a cell adhesion/recognition molecule of the immunoglobulin superfamily implicated in axonal growth. We examined its subcellular distribution and mobilization to the cell surface in oxytocin- (OT-) secreting neurons, which express it throughout life and the axons of which undergo activity-dependent remodelling. This was performed in hypothalamic organotypic slice cultures containing OT neurons with properties of adult neurosecretory cells. Immunocytochemistry and immunoblot… CONTINUE READING

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