Mobilization of hematopoietic stem/progenitor cells: general principles and molecular mechanisms.

@article{Bonig2012MobilizationOH,
  title={Mobilization of hematopoietic stem/progenitor cells: general principles and molecular mechanisms.},
  author={Halvard B Bonig and T. Papayannopoulou},
  journal={Methods in molecular biology},
  year={2012},
  volume={904},
  pages={1-14}
}
Hematopoietic stem/progenitor cell mobilization can be achieved by a variety of bone marrow niche modifications, although efficient mobilization requires simultaneous expansion of the stem/progenitor cell pool and niche modification. Many of the mechanisms involved in G-CSF-induced mobilization have been described. With regard to mobilization of hematopoietic stem/progenitor cells, challenges for the future include the analysis of genetic factors responsible for the great variability in… CONTINUE READING

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