Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils.

@article{Sengelv1995MobilizationOG,
  title={Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils.},
  author={Henrik Sengel\ov and P. H. Follin and Lars Kjeldsen and Karsten Lollike and Claes Dahlgren and Neils Borregaard},
  journal={Journal of immunology},
  year={1995},
  volume={154 8},
  pages={4157-65}
}
The extent of mobilization of four different intracellular compartments was measured during in vivo exudation of neutrophils into skin chambers and compared with resting neutrophils obtained from blood. Exudation of neutrophils induced increased surface expression of alkaline phosphatase, complement receptor 1, and Mac-1, and a complete loss of L-selectin. The increase in the content of surface molecules in the plasma membrane is in accordance with complete mobilization of secretory vesicles… CONTINUE READING
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