Mobility of green fluorescent protein in hydrogel-based drug-delivery systems studied by anisotropy and fluorescence recovery after photobleaching.


Modified hydroxyethyl starch is photo-crosslinked in the presence of a green fluorescent protein (GFP) (mTagGFP) to obtain loaded hydrogels as model for a drug-delivery system. An important factor for the protein release is the crosslinking density since a dense network should lead to hindered diffusion. To obtain information on the rotational and… (More)
DOI: 10.1002/mabi.201200325


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