• DOI:10.1016/0006-8993(90)91379-U
Corpus ID: 25701458

Mn and Mg influxes through Ca channels of motor nerve terminals are prevented by verapamil in frogs

@article{Narita1990MnAM,
  title={Mn and Mg influxes through Ca channels of motor nerve terminals are prevented by verapamil in frogs},
  author={K. Narita and F. Kawasaki and H. Kita},
  journal={Brain Research},
  year={1990},
  volume={510},
  pages={289-295}
}

K. Narita, F. Kawasaki, H. Kita

Published 1990

Chemistry, Medicine

Brain Research

At frog neuromuscular junctions immersed in solutions containing 0.5 mM Mn2+, verapamil (40 microM) reduced the increase in miniature end-plate potential (MEPP) frequency produced by tetanic stimulation (50 Hz, 2 min) of the motor nerve to 5% of that in the absence of verapamil. In solutions containing 5 mM Mg2+, verapamil reduced the tetanic increase in MEPP frequency to 8% of that in the absence of verapamil. Verapamil added to solutions containing 0.15 mM Ca2+ decreased the tetanic rise in… CONTINUE READING

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