Mixture designs to assess composition–structure–property relationships in SiO2–CaO–ZnO–La2O3–TiO2–MgO–SrO–Na2O glasses: Potential materials for embolization

  title={Mixture designs to assess composition–structure–property relationships in SiO2–CaO–ZnO–La2O3–TiO2–MgO–SrO–Na2O glasses: Potential materials for embolization},
  author={Sharon Kehoe and Maxine Langman and Ulli Werner-Zwanziger and Robert J. Abraham and Daniel Boyd},
  journal={Journal of Biomaterials Applications},
  pages={416 - 433}
Embolization with micron-sized particulates is widely applied to treat uterine fibroids. The objective of this work was to develop mixture designs to predict materials composition–structure–property relationships for the SiO2–CaO–ZnO–La2O3–TiO2–MgO–SrO–Na2O glass system and compare its fundamental materials properties (density and cytocompatibility), against a state-of-the-art embolic agent (contour polyvinyl alcohol) to assess the potential of these materials for embolization therapies. The… 
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Composition-property relationships for radiopaque composite materials: pre-loaded drug-eluting beads for transarterial chemoembolization
It was possible to preload doxorubicin into radiopaque composite drug-eluting beads, such that sustained release was possible under simulated physiological conditions and the mathematical models allowed for the identification and synthesis of a unique radiopaques composite.
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The effect of ionic dissolution products of Ca–Sr–Na–Zn–Si bioactive glass on in vitro cytocompatibility
Results indicate that the calcium–strontium–sodium–zinc–silicate glass compositions show equivalent or even enhanced in vitro compatibility compared to Novabone®.
Composition–property relationships for an experimental composite nerve guidance conduit: evaluating cytotoxicity and initial tensile strength
The experimental conduits generally showed superior cytocompatibility when compared with the comparable literature for the clinically used nerve guidance conduit Neurolac®, and shows that the materials examined may have potential for the repair of peripheral nerve discontinuities.
The processing, mechanical properties and bioactivity of zinc based glass ionomer cements
  • D. Boyd, M. Towler
  • Materials Science
    Journal of materials science. Materials in medicine
  • 2005
The purpose of this research was to produce novel GICs based on calcium zinc silicate glasses and to evaluate their rheological, mechanical and biocompatible properties with the ultimate objective of developing a new range of cements for skeletal applications.
A structural study of (TiO2)x(SiO2)1–x (x=0.18, 0.30 and 0.41) xerogels prepared using acetylacetone
A combination of 29 Si and 17 O MAS NMR, EXAFS and FTIR spectroscopy have been used to study the atomic structure of (TiO 2 ) x (SiO 2 ) 1–x (x=0.18, 0.30 and 0.41) xerogels prepared