Mixed-type inhibition of tyrosinase from Agaricus bisporus by terephthalic acid: computational simulations and kinetics.

@article{Yin2011MixedtypeIO,
  title={Mixed-type inhibition of tyrosinase from Agaricus bisporus by terephthalic acid: computational simulations and kinetics.},
  author={Shang-jun Yin and Yue-Xiu Si and Y Chen and Guo-ying Qian and Zhi-Rong L{\"u} and Sangho Oh and Jinhyuk Lee and Sanghyuk Lee and J. Yang and Dong-Youn Lee and Y C Park},
  journal={The protein journal},
  year={2011},
  volume={30 4},
  pages={273-80}
}
Tyrosinase inhibition studies are needed due to the agricultural and medicinal applications. For probing effective inhibitors of tyrosinase, a combination of computational prediction and enzymatic assay via kinetics were important. We predicted the 3D structure of tyrosinase from Agaricus bisporus, used a docking algorithm to simulate binding between… CONTINUE READING