Mixed-matrix membrane adsorbers for protein separation.

  title={Mixed-matrix membrane adsorbers for protein separation.},
  author={M E Avramescu and Zandrie Borneman and Matthias Wessling},
  journal={Journal of chromatography. A},
  volume={1006 1-2},
The separation of two similarly sized proteins, bovine serum albumin (BSA) and bovine hemoglobin (Hb) was carried out using a new type of ion-exchange mixed-matrix adsorber membranes. The adsorber membranes were prepared by incorporation of various types of Lewatit ion-exchange resins into an ethylene-vinyl alcohol copolymer porous structure. The obtained heterogeneous matrices, composed of solid particles surrounded by the polymeric film, display high static and dynamic protein adsorption… CONTINUE READING