Mixed cryoglobulinemia: clinical aspects and long-term follow-up of 40 patients.

@article{Gorevic1980MixedCC,
  title={Mixed cryoglobulinemia: clinical aspects and long-term follow-up of 40 patients.},
  author={Peter D. Gorevic and H J Kassab and Yoram Levo and Robert Kohn and Michele Meltzer and Philip H. Prose and Edward C. Franklin},
  journal={The American journal of medicine},
  year={1980},
  volume={69 2},
  pages={287-308}
}
The clinical course of 40 patients with significant quantities of mixed cryoglobulins, but without lymphoproliferative, collagen-vascular or chronic infectious diseases, is presented. These cases comprise 51.3 percent of all mixed and 31.7 percent of all types of cryoglobulins evaluated by us over the period 1960--1978. A characteristic clinical syndrome, consisting of recurrent palpable purpura (100 percent), polyarthralgias (72.5 percent) and renal disease (55 percent), was seen. Biopsy… CONTINUE READING
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