Mixed acinar-endocrine carcinomas of the pancreas.

  title={Mixed acinar-endocrine carcinomas of the pancreas.},
  author={David S. Klimstra and Juan Rosai and Clara S. Heffess},
  journal={The American journal of surgical pathology},
  volume={18 8},
Acinar cell carcinoma is a rare pancreatic neoplasm that may contain scattered endocrine cells in as many as 40% of cases. In addition, unusual tumors exist in which the acinar and endocrine components each constitute a significant proportion (> 25%) of the neoplasm; we propose to designate them as "mixed acinar-endocrine carcinomas." In a study of five such cases, we found one case with segregated areas of acinar and endocrine cells that were identifiable in routinely stained sections and four… CONTINUE READING

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