Mixed Phenotype Acute Leukemia with t(12;17)(p13;q21)/TAF15-ZNF384 and Other Chromosome Abnormalities.

@article{Yamamoto2016MixedPA,
  title={Mixed Phenotype Acute Leukemia with t(12;17)(p13;q21)/TAF15-ZNF384 and Other Chromosome Abnormalities.},
  author={Katsuya Yamamoto and Shinichiro Kawamoto and Yu Mizutani and Kimikazu Yakushijin and Tomoe Yamashita and Yuji Nakamachi and Seiji Kawano and Yoshitake Hayashi and Hiroshi Matsuoka and Hironobu Minami},
  journal={Cytogenetic and genome research},
  year={2016},
  volume={149 3},
  pages={165-170}
}
The t(12;17)(p13;q11∼21) translocation is a very rare but recurrent cytogenetic aberration observed predominantly in early pre-B acute lymphoblastic leukemia (ALL) with CD19+CD10-CD33+ phenotype. This translocation was shown to form a fusion gene between TAF15 at 17q12 and ZNF384 at 12p13. On the other hand, der(1;18)(q10;q10) has been detected as a rare… CONTINUE READING