Mitsugumin 29 regulates t-tubule architecture in the failing heart

Abstract

Transverse tubules (t-tubules) are uniquely-adapted membrane invaginations in cardiac myocytes that facilitate the synchronous release of Ca2+ from internal stores and subsequent myofilament contraction, although these structures become disorganized and rarefied in heart failure. We previously observed that mitsugumin 29 (Mg29), an important t-tubule… (More)
DOI: 10.1038/s41598-017-05284-2

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