Mitral insufficiency caused by systemic lupus erythematosus requiring valve replacement: three case reports and a review of the literature.

@article{Morin1996MitralIC,
  title={Mitral insufficiency caused by systemic lupus erythematosus requiring valve replacement: three case reports and a review of the literature.},
  author={Andr{\'e} Morin and Amanda Boyer and Patrick R Nataf and Iradj Gandjbakhch},
  journal={The Thoracic and cardiovascular surgeon},
  year={1996},
  volume={44 6},
  pages={313-6}
}
The increase of mitral valve insufficiency associated with systemic lupus erythematosus (SLE) seems to be related to the treatment with corticosteroids. Corticosteroids heal Libman-Sacks endocarditis, but thereby they lead to fibrotic, retracted leaflet tissue and thus to severe valvular dysfunction. We present three patients with SLE who underwent mitral valve replacement due to severe mitral insufficiency. All had been treated with corticosteroids for several years prior to the surgical… CONTINUE READING
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