Mitral Valve Prolapse With a Late-Systolic Regurgitant Murmur May Be Associated With Significant Hemodynamic Consequences

  title={Mitral Valve Prolapse With a Late-Systolic Regurgitant Murmur May Be Associated With Significant Hemodynamic Consequences},
  author={Mustafa Iltimas Ahmed and Thriveni Sanagala and Thomas S. Denney and Seidu Inusah and David C McGiffin and Donald Knowlan and Robert A. O'rourke and Louis J. Dell’Italia},
  journal={The American Journal of the Medical Sciences},
The late-systolic murmur of mitral regurgitation (MR) in degenerative mitral valve disease is widely believed to represent regurgitation of a degree that is not associated with hemodynamic significance. However, the extent of left ventricular (LV) remodeling associated with the late-systolic murmur has not been systematically assessed. Accordingly, we studied 82 patients sent for evaluation of at least moderate isolated MR by echocardiography/Doppler examination. All patients had a physical… 

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Mitral Valve Prolapse

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