Mitotic sympathetic neuroblasts initiate axonal pathfinding in vivo.

  title={Mitotic sympathetic neuroblasts initiate axonal pathfinding in vivo.},
  author={Eva Wolf and Ira B. Black and Emanuel Dicicco-Bloom},
  journal={Journal of neurobiology},
  volume={40 3},
Neuronal precursor proliferation and axodendritic outgrowth have been traditionally regarded as discrete and sequential developmental stages. However, we recently found that sympathetic neuroblasts in vitro often elaborate long neuritic processes before dividing. Furthermore, these "paramitotic" neurites were maintained during cell division and neuritic morphology was consistently preserved by daughter cells after mitosis. This inheritance of neuritic morphology in vitro raised the possibility… CONTINUE READING

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