Mitotic spindle morphogenesis: Ran on the microtubule cytoskeleton and beyond.

@article{Goodman2006MitoticSM,
  title={Mitotic spindle morphogenesis: Ran on the microtubule cytoskeleton and beyond.},
  author={Benjamin Goodman and Yixian Zheng},
  journal={Biochemical Society transactions},
  year={2006},
  volume={34 Pt 5},
  pages={716-21}
}
Assembly and disassembly of the mitotic spindle are essential for both chromosome segregation and cell division. The small G-protein Ran has emerged as an important regulator of spindle assembly. In this review, we look at the role of Ran in different aspects of spindle assembly, including its effects on microtubule assembly dynamics and microtubule organization. In addition, we examine the possibility of a spindle matrix and the role Ran might play in such a structure. 

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
22 Extracted Citations
19 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 22 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 19 references

Curr. Biol

  • H Sillje, S Nagel, R Korner, E Nigg
  • Curr. Biol
  • 2006

Nat. Rev. Mol. Cell Biol

  • V Schreiber, F Dantzer, J Ame, G De Murcia
  • Nat. Rev. Mol. Cell Biol
  • 2006

Cell

  • M D Blower, M Nachury, R Heald, K Weis
  • Cell
  • 2005

J. Cell Biol

  • T P Barros, K Kinoshita, A A Hyman, J W Raff
  • J. Cell Biol
  • 2005

Mol. Cell. Biol

  • C R Yu, J Hsu, Y G Lee, A Tsou, C Chou, C F Huang
  • Mol. Cell. Biol
  • 2005

Nat. Cell Biol

  • P Chang, M Coughlin, T J Mitchison
  • Nat. Cell Biol
  • 2005

Nature

  • S J Royle, N A Bright, L Lagnado
  • Nature
  • 2005

Science

  • Q P Vong, K Cao, H Y Li, P A Iglesias, Y Zheng
  • Science
  • 2005

J. Biol. Chem

  • J Hsu, Y G Lee, C R Yu, C F Huang
  • J. Biol. Chem
  • 2004

J. Cell Biochem. Mol. Biol. Cell

  • U Rath, D Wang, +6 authors K M Johansen
  • J. Cell Biochem. Mol. Biol. Cell
  • 2004

Similar Papers

Loading similar papers…