Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

@article{Taguchi2007MitoticPO,
  title={Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.},
  author={Naoko Taguchi and Naotada Ishihara and Akihiro Jofuku and Toshihiko Oka and Katsuyoshi Mihara},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 15},
  pages={11521-9}
}
Organelles are inherited to daughter cells beyond dynamic changes of the membrane structure during mitosis. Mitochondria are dynamic entities, frequently dividing and fusing with each other, during which dynamin-related GTPase Drp1 is required for the fission reaction. In this study, we analyzed mitochondrial dynamics in mitotic mammalian cells. Although mitochondria in interphase HeLa cells are long tubular network structures, they are fragmented in early mitotic phase, and the filamentous… CONTINUE READING
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