Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint.

Abstract

The spindle checkpoint prevents activation of the anaphase-promoting complex (APC/C) until all chromosomes are correctly attached to the mitotic spindle. Early in mitosis, the mitotic checkpoint complex (MCC) inactivates the APC/C by binding the APC/C activating protein CDC20 until the chromosomes are properly aligned and attached to the mitotic spindle, at… (More)
DOI: 10.1080/15384101.2015.1121331

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Cite this paper

@article{Foss2016MitoticPA, title={Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint.}, author={Kristen M Foss and Alexander C. Robeson and Sally Kornbluth and Liguo Zhang}, journal={Cell cycle}, year={2016}, volume={15 2}, pages={225-33} }