Mitotic drivers—inhibitors of the Aurora B Kinase

@article{Keen2009MitoticDO,
  title={Mitotic drivers—inhibitors of the Aurora B Kinase},
  author={N. Keen and Stephen S Taylor},
  journal={Cancer and Metastasis Reviews},
  year={2009},
  volume={28},
  pages={185-195}
}
In this article we review the basis for current anti-mitotic, anti-cancer, therapy and the potential for Aurora B kinase inhibitors as a new differentiated class of agents—“mitotic drivers”. We review the current understanding of Aurora B inhibition from basic cell biology to inhibitors currently undergoing clinical trials. 
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