Mitotane treatment in patients with metastatic testicular Leydig cell tutor associated with severe androgen excess.

Abstract

Mitotane (o,p'DDD) is established in the adjuvant and advanced stage treatment of adrenocortical carcinoma and counteracts both tumour growth and tumour-related steroid production. Both the adrenal glands and the gonads are steroidogenically active organs and share a common embryogenic origin. Here we describe the effects of mitotane in two patients with… (More)
DOI: 10.1530/EJE-17-0542

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Cite this paper

@article{Chortis2018MitotaneTI, title={Mitotane treatment in patients with metastatic testicular Leydig cell tutor associated with severe androgen excess.}, author={Vasileios Chortis and Nicholas J Johal and Irina Bancos and Matthew Evans and Kassiani Skordilis and Peter J Guest and M. Cullen and Emilio Porfiri and Wiebke Arlt}, journal={European journal of endocrinology}, year={2018} }