Mitosis Detection in Intestinal Crypt Images with Hough Forest and Conditional Random Fields

  title={Mitosis Detection in Intestinal Crypt Images with Hough Forest and Conditional Random Fields},
  author={Gerda Bortsova and Michael Sterr and Lichao Wang and Fausto Milletari and Nassir Navab and Anika B{\"o}ttcher and Heiko Lickert and Fabian J Theis and Tingying Peng},
Intestinal enteroendocrine cells secrete hormones that are vital for the regulation of glucose metabolism but their differentiation from intestinal stem cells is not fully understood. Asymmetric stem cell divisions have been linked to intestinal stem cell homeostasis and secretory fate commitment. We monitored cell divisions using 4D live cell imaging of cultured intestinal crypts to characterize division modes by means of measurable features such as orientation or shape. A statistical analysis… 


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  • N. Barker
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