Mitogenic and antimitogenic transforming growth factors secreted by adenovirus 2- and simian virus 40-transformed hamster cells: possible roles in promoting tumorigenesis.

Abstract

Adenovirus 2 (Ad2)- and simian virus 40 (SV40)-transformed hamster embryo cells differ markedly in a number of phenotypic properties including their potential for inducing tumors in hamsters. Both Ad2- and SV40-transformed cells are immortalized and readily induce tumors in immunoincompetent newborn syngeneic hamsters, but only SV40-transformed cells are… (More)

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@article{Akagi1987MitogenicAA, title={Mitogenic and antimitogenic transforming growth factors secreted by adenovirus 2- and simian virus 40-transformed hamster cells: possible roles in promoting tumorigenesis.}, author={Kiwamu Akagi and Kazunori Murai and H{\'e}di Haddada and Allen Stuart Levine and Cephas T. Patch}, journal={Cancer research}, year={1987}, volume={47 15}, pages={4086-92} }