Mitogenic activity of laminin on human melanoma and melanocytes: different signal requirements and role of beta 1 integrins.

@article{Mortarini1995MitogenicAO,
  title={Mitogenic activity of laminin on human melanoma and melanocytes: different signal requirements and role of beta 1 integrins.},
  author={Roberta Mortarini and Angela Angela Gismondi and Aldo Pietro Maggioni and Angela Santoni and Meenhard Herlyn and Andrea Anichini},
  journal={Cancer research},
  year={1995},
  volume={55 20},
  pages={4702-10}
}
The possible mitogenic activity of laminin (LN) on normal and neoplastic cells of the melanocyte lineage was tested by culturing growth-arrested human melanoma cells and neonatal foreskin melanocytes on LN. Serum-deprived, quiescent melanoma cells proliferated, in serum-free medium, in a dose-dependent fashion to immobilized LN as determined by [3H… CONTINUE READING