Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virus.

Abstract

The induction of the intrinsic antiviral defense in mammals relies on the accumulation of foreign genetic material. As such, complete engagement of this response is limited to replication-competent viruses. Interferon regulatory factors (IRFs) are mediators of this defense with shared enhancer elements but display a spectrum of transcriptional potential… (More)
DOI: 10.1074/jbc.M113.519934

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Cite this paper

@article{Schmid2014MitogenactivatedPK, title={Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virus.}, author={Sonja Schmid and David Sachs and Benjamin R tenOever}, journal={The Journal of biological chemistry}, year={2014}, volume={289 1}, pages={299-311} }