Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer

@inproceedings{Li2015MitogenactivatedPK,
  title={Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer},
  author={Dongmei Li and Jun Zhang and Yu Xi and Lei Zhang and Wenmei Li and Jiantao Cui and Rui Xing and Yuanmin Pan and Zemin Pan and Feng Li and Youyong Lu},
  booktitle={BMC Cancer},
  year={2015}
}
Our previous proteomic analysis revealed that mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein (MAWBP) were downregulated in gastric cancer (GC) tissues. These proteins interacted and formed complexes in GC cells. To investigate the role of MAWD and MAWBP in GC differentiation, we analyzed the relationship between MAWD/MAWBP and clinicopathologic characteristics of GC tissues and examined the expression of E-cadherin and pepsinogen C (PGC)—used as… CONTINUE READING

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MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.

World journal of gastroenterology • 2013
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