Mitogen-activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP-9) in breast epithelial cells.

Abstract

Mitogen-activated protein kinases (MAPKs) play a major role in the mitogenic signal transduction pathway and are essential components of both growth and differentiation. Constitutive activation of the MAPK cascade is associated with the carcinogenesis and metastasis of human breast and renal cell carcinomas. The gelatinases B (MMP-9) and A (MMP-2) are 2… (More)

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Cite this paper

@article{Reddy1999MitogenactivatedPK, title={Mitogen-activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP-9) in breast epithelial cells.}, author={K. Vijaya Bhaskar Reddy and J. Kr{\"u}ger and Sudhir B. Kondapaka and Clement A. Diglio}, journal={International journal of cancer}, year={1999}, volume={82 2}, pages={268-73} }