Mitogen-Activated Protein Kinases and Hypoxic/Ischemic Nephropathy

  title={Mitogen-Activated Protein Kinases and Hypoxic/Ischemic Nephropathy},
  author={Fengbao Luo and Jian-Ting Shi and Qianqian Shi and Xianlin Xu and Ying Xia and Xiaozhou He},
  journal={Cellular Physiology and Biochemistry},
  pages={1051 - 1067}
Tissue hypoxia/ischemia is a pathological feature of many human disorders including stroke, myocardial infarction, hypoxic/ischemic nephropathy, as well as cancer. In the kidney, the combination of limited oxygen supply to the tissues and high oxygen demand is considered the main reason for the susceptibility of the kidney to hypoxic/ischemic injury. In recent years, increasing evidence has indicated that a reduction in renal oxygen tension/blood supply plays an important role in acute kidney… 

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