Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology

@inproceedings{Lloberas2016MitogenActivatedPK,
  title={Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology},
  author={Jorge Lloberas and Lorena Valverde-Estrella and Juan Benito Tur and Tania Vico and Antonio Rodr{\'i}guez Celada},
  booktitle={Front. Mol. Biosci.},
  year={2016}
}
Macrophages are necessary in multiple processes during the immune response or inflammation. This review emphasizes the critical role of the mitogen-activated protein kinases (MAPKs) and mitogen kinase phosphatase-1 (MKP-1) in the functional activities of macrophages. While the phosphorylation of MAPKs is required for macrophage activation or proliferation, MKP-1 dephosphorylates these kinases, thus playing a balancing role in the control of macrophage behavior. MKP-1 is a nuclear-localized dual… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 82 REFERENCES

Macrophage colony

A. F. Valledor, J. Xaus, L. Marques, A. Celada
  • J. Immunol
  • 1999
VIEW 6 EXCERPTS
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