Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism.

@article{Fryland1997MitochondrionIT,
  title={Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism.},
  author={Livar Fr\oyland and Lise Madsen and Hege Vaagenes and Geir K{\aa}re Totland and Johan Auwerx and Harald Kryvi and Bart Staels and Rolf Kristian Berge},
  journal={Journal of lipid research},
  year={1997},
  volume={38 9},
  pages={1851-8}
}
Fish oil polyunsaturated fatty acids and fibrate hypolipidemic drugs are potent hypotriglyceridemic agents that act by increasing fatty acid catabolism and decreasing triglyceride synthesis and secretion by the liver. A major unresolved issue is whether this hypotriglyceridemic effect can occur independent of induction of peroxisomal beta-oxidation, a predisposing factor for hepatocarcinogenesis. The present study was undertaken to determine which component of fish oil, eicosapentaenoic acid… CONTINUE READING

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