Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching

Abstract

Mitochondrial uncoupling protein 2 (UCP2) is an integral membrane protein in the mitochondrial anion carrier protein family, the members of which facilitate the transport of small molecules across the mitochondrial inner membrane. When the mitochondrial respiratory complex pumps protons from the mitochondrial matrix to the intermembrane space, it builds up… (More)
DOI: 10.1038/nature10257

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