Mitochondrial uncoupling agents trigger ventricular fibrillation in isolated rat hearts.

Abstract

Sudden cardiac death resulting from ventricular fibrillation (VF) remains a major cause of mortality. The purpose of this study was to investigate the roles of loss of oxidative phosphorylation and activation of the mitochondrial ATP-sensitive K+ channel and permeability transition pore in VF development during myocardial ischemia by using mitochondrial… (More)
DOI: 10.1097/FJC.0b013e31820d5342

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