Mitochondrial transport dynamics in axons and dendrites.

  title={Mitochondrial transport dynamics in axons and dendrites.},
  author={Konrad E. Zinsmaier and Milos Babic and Gary J Russo},
  journal={Results and problems in cell differentiation},
Mitochondrial dynamics and transport have emerged as key factors in the regulation of neuronal differentiation and survival. Mitochondria are dynamically transported in and out of axons and dendrites to maintain neuronal and synaptic function. Transport proceeds through a controlled series of plus- and minus-end directed movements along microtubule tracks (MTs) that are often interrupted by short stops. This bidirectional motility of mitochondria is facilitated by plus end-directed kinesin and… CONTINUE READING

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