Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia.

@article{Jezek2009MitochondrialRN,
  title={Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia.},
  author={Petr Jezek and Lydie Plecit{\'a}-Hlavat{\'a}},
  journal={The international journal of biochemistry & cell biology},
  year={2009},
  volume={41 10},
  pages={1790-804}
}
A single mitochondrial network in the cell undergoes constant fission and fusion primarily depending on the local GTP gradients and the mitochondrial energetics. Here we overview the main properties and regulation of pro-fusion and pro-fission mitodynamins, i.e. dynamins-related GTPases responsible for mitochondrial shape-forming, such as pro-fusion mitofusins MFN1, MFN2, and the inner membrane-residing long OPA1 isoforms, and pro-fission mitodynamins FIS1, MFF, and DRP1 multimers required for… CONTINUE READING
36 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Similar Papers

Loading similar papers…