Mitochondrial response to heart rate steps in isolated rabbit heart is slowed after myocardial stunning.

@article{Zuurbier1997MitochondrialRT,
  title={Mitochondrial response to heart rate steps in isolated rabbit heart is slowed after myocardial stunning.},
  author={Coert J Zuurbier and Johannes H G M van Beek},
  journal={Circulation research},
  year={1997},
  volume={81 1},
  pages={69-75}
}
The oxidative capacity of mitochondria isolated from myocardium is undiminished after myocardial stunning, which is remarkable because stunning affects many other cellular functions. The aim of the present study was to assess the mitochondrial oxidative response in intact rather than isolated myocardium. The mean response time of mitochondrial O2 consumption to heart rate steps (tmito) was measured before and after 15-minute ischemia or high-flow hypoxia in isolated rabbit hearts. The tmito was… CONTINUE READING