Mitochondrial replacement therapies can circumvent mtDNA-based disease transmission.

@article{Wolf2014MitochondrialRT,
  title={Mitochondrial replacement therapies can circumvent mtDNA-based disease transmission.},
  author={Don P Wolf and Shoukhrat Mitalipov},
  journal={Cell metabolism},
  year={2014},
  volume={20 1},
  pages={
          6-8
        }
}
Mitochondrial DNA diseases are relatively common, sometimes devastating, and transmitted exclusively through the egg to children of carrier mothers. A study in Cell by Wang et al. (2014) adds the exciting possibility of a new therapy for preventing mitochondrial disease transmission predicated on the use of polar body genomes in mice. 
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