Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF).

Abstract

Apoptosis might proceed through the activation of both caspase-dependent and -independent pathways. Apoptosis-inducing factor (AIF) was discovered as the first protein that mediated caspase-independent cell death. Initially, it was regarded as a soluble protein residing in the intermembrane space of mitochondria, from where it could be exported to the… (More)
DOI: 10.1016/j.bbrc.2010.02.163

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Cite this paper

@article{Norberg2010MitochondrialRO, title={Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF).}, author={Erik Norberg and Sten Orrenius and Boris Zhivotovsky}, journal={Biochemical and biophysical research communications}, year={2010}, volume={396 1}, pages={95-100} }