Mitochondrial regulation of cell cycle and proliferation.

  title={Mitochondrial regulation of cell cycle and proliferation.},
  author={Valeria Gabriela Antico Arciuch and Mar{\'i}a Eugenia Elguero and Juan Jos{\'e} Poderoso and Mar{\'i}a Cecilia Carreras},
  journal={Antioxidants & redox signaling},
  volume={16 10},
Eukaryotic mitochondria resulted from symbiotic incorporation of α-proteobacteria into ancient archaea species. During evolution, mitochondria lost most of the prokaryotic bacterial genes and only conserved a small fraction including those encoding 13 proteins of the respiratory chain. In this process, many functions were transferred to the host cells, but mitochondria gained a central role in the regulation of cell proliferation and apoptosis, and in the modulation of metabolism; accordingly… CONTINUE READING


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