Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.

@article{Zorov2014MitochondrialRO,
  title={Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.},
  author={Dmitry B. Zorov and Magdalena Juhaszova and Steven J. Sollott},
  journal={Physiological reviews},
  year={2014},
  volume={94 3},
  pages={909-50}
}
Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of potentially damaging levels of reactive oxygen species (ROS), Ca(2+), etc., which must be normalized. Evidence suggests that brief mitochondrial permeability transition pore (mPTP) openings play an important physiological role maintaining healthy mitochondria homeostasis. Adaptive and maladaptive responses to redox stress may involve mitochondrial channels such as mPTP and inner membrane anion channel (IMAC… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 496 references

Principles of Bioenergetics

VP Skulachev, AV Bogachev, FO. Kasparinsky
Berlin: Springer-Verlag, • 2013
View 7 Excerpts
Highly Influenced

Mitochondrial oscillations in physiology and pathophysiology.

Advances in experimental medicine and biology • 2008
View 17 Excerpts
Highly Influenced

The role of mitochondria in reactive oxygen species metabolism and signaling.

Annals of the New York Academy of Sciences • 2008
View 10 Excerpts
Highly Influenced

Generation of superoxide by the mitochondrial Complex I.

Biochimica et biophysica acta • 2006
View 5 Excerpts
Highly Influenced

The inactivation of Fe-S cluster containing hydro-lyases by superoxide.

The Journal of biological chemistry • 1993
View 20 Excerpts
Highly Influenced

Calcium release from the sarcoplasmic reticulum.

Biophysical journal • 1987
View 10 Excerpts
Highly Influenced

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