Mitochondrial proteomics in experimental autoimmune uveitis oxidative stress.

@article{Saraswathy2009MitochondrialPI,
  title={Mitochondrial proteomics in experimental autoimmune uveitis oxidative stress.},
  author={Sindhu Saraswathy and Narsing Adupa Rao},
  journal={Investigative ophthalmology & visual science},
  year={2009},
  volume={50 12},
  pages={5559-66}
}
PURPOSE Photoreceptor mitochondrial oxidative stress is the initial pathologic event in experimental autoimmune uveitis. In this study, the authors determined alterations in retinal mitochondrial protein levels in response to oxidative stress during the early phase of experimental autoimmune uveitis (EAU). METHODS Retinal mitochondrial fractions during early EAU were prepared and subjected to two-dimensional difference in gel electrophoresis (2D-DIGE). Protein spots showing differential… CONTINUE READING
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