Mitochondrial porin can be translocated across both endoplasmic reticulum and mitochondrial membranes.

@article{Sakaguchi1992MitochondrialPC,
  title={Mitochondrial porin can be translocated across both endoplasmic reticulum and mitochondrial membranes.},
  author={Masao Sakaguchi and Naomi Hachiya and Katsuyoshi Mihara and Toshihiro Omura},
  journal={Journal of biochemistry},
  year={1992},
  volume={112 2},
  pages={243-8}
}
Mitochondrial porin is a major integral membrane protein of the outer membrane. To assess the stop-transfer sequence in the yeast porin molecule (P), we constructed the following chimeric proteins. (i) The signal sequence of interleukin 2, a secretory protein, was fused to the amino-terminus of porin (SP). (ii) The matrix targeting presequence of cytochrome c oxidase subunit IV was fused to the amino-terminus of porin (CP). (iii) The amino-terminal segment consisting of 42 amino acid residues… CONTINUE READING