Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells.


Here, we have investigated the role of inorganic phosphate (Pi) transport in mitochondria of rat clonal β-cells. In α-toxin-permeabilized INS-1E cells, succinate and glycerol-3-phosphate increased mitochondrial ATP release which depends on exogenous ADP and Pi. In the presence of substrates, addition of Pi caused mitochondrial matrix acidification and… (More)
DOI: 10.1016/j.mce.2013.08.003


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